Hi there. I'm a developmental biologist who went into genomics a few years ago. I had been trained intried-and-true assays: lots of in situ hybridizations, fate-mapping with fluorescent dextrans, confocal imaging, that sort of thing. I traded these approaches for molecular biology methods development, learning to properly do bioinformatics, and a complete revision of my thinking to intellectually accommodate the billions of measurements I was suddenly taking.
My research these days focuses on using and generating genomics tools to tackle basic questions about how we get different cell types. How much cellular machinery determines one cell type from another? Why is that machinery turned on in some cells but not others? Can we understand the machinery well enough to make predictions about what happens when it breaks?